| 000 | 02778nab a2200409 c 4500 | ||
|---|---|---|---|
| 001 | koha000927404 | ||
| 005 | 20230228181310.0 | ||
| 007 | cr | | ||
| 008 | 230123|2022 sz s a eng d | ||
| 024 | 7 |
_a10.3390/photonics9030199 _2doi |
|
| 035 | _akoha000927404 | ||
| 040 |
_aRU-ToGU _brus _cRU-ToGU |
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| 245 | 1 | 0 |
_aChanges in optical properties of model cholangiocarcinoma after plasmon-resonant photothermal treatment _cV. D. Genin, A. B. Bucharskaya, G. S. Terentyuk [et al.] |
| 336 | _aТекст | ||
| 337 | _aэлектронный | ||
| 504 | _aБиблиогр.: 44 назв. | ||
| 520 | 3 | _aThe heating degree of the inner layers of tumor tissue is an important parameter required to optimize plasmonic photothermal therapy (PPT). This study reports the optical properties of tissue layers of transplanted cholangiocarcinoma and covering tissues in rats without treatment (control group) and after PPT using gold nanorods (experimental group). PPT was carried out for 15 min, and the temperature on the skin surface reached 54.8 1.6 C. The following samples were cut out ex vivo and studied: skin, subcutaneous connective tissue, tumor capsule, top, center, and bottom part of the tumor. The samples’ absorption and reduced scattering coefficients were calculated using the inverse adding–doubling method at 350–2250 nm wavelength. Diffuse reflectance spectra of skin surface above tumors were measured in vivo in the control and experimental groups before and immediately after PPT in the wavelength range of 350–2150 nm. Our results indicate significant differences between the optical properties of the tissues before and after PPT. The differences are attributed to edema and hemorrhage in the surface layers, tissue dehydration of the deep tumor layers, and morphological changes during the heating. | |
| 653 | _aзолотые наностержни | ||
| 653 | _aплазмонная фототермическая терапия | ||
| 653 | _aоптические свойства | ||
| 653 | _aтрансплантированные опухоли | ||
| 653 | _aмодели опухолей | ||
| 653 | _aхолангиокарцинома | ||
| 655 | 4 |
_aстатьи в журналах _9857891 |
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| 700 | 1 |
_aGenin, Vadim D. _9504588 |
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| 700 | 1 |
_aBucharskaya, Alla B. _9113426 |
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| 700 | 1 |
_aTerentyuk, Georgy S. _9337941 |
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| 700 | 1 |
_aKhlebtsov, Nikolay G. _9106606 |
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| 700 | 1 |
_aNavolokin, Nikita A. _9113427 |
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| 700 | 1 |
_aTuchin, Valery V. _978712 |
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| 700 | 1 |
_aGenina, Elina A. _9113421 |
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| 773 | 0 |
_tPhotonics _d2022 _gVol. 9, № 3. P. 199 (1-13) _x2304-6732 |
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| 852 | 4 | _aRU-ToGU | |
| 856 | 4 | _uhttp://vital.lib.tsu.ru/vital/access/manager/Repository/koha:000927404 | |
| 908 | _aстатья | ||
| 999 | _c927404 | ||