| 000 | 02190naa a2200385 c 4500 | ||
|---|---|---|---|
| 001 | vtls000662058 | ||
| 003 | RU-ToGU | ||
| 005 | 20221026151903.0 | ||
| 007 | cr | | ||
| 008 | 190912s2018 ru fs 100 0 eng d | ||
| 035 | _ato000662058 | ||
| 040 |
_aRU-ToGU _brus _cRU-ToGU |
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| 245 | 1 | 0 |
_aCirculating DNA-markers in lung cancer: changes in retrotrasposons methylation status in response therapy and during the post-treatment follow-up _cA. A. Ponomaryova, A. Y. Dobrodeev, A. A. Bondar [et.al.] |
| 504 | _aБиблиогр.: 4 назв. | ||
| 520 | 3 | _aMalignant cell transformation is accompanied by two processes of DNA methylation changes: hypermethylation in CpG islands of tumor suppressor genes and global hypomethylation in repetitive DNA sequences (retrotransposons) [1, 2]. The composition of circulating DNA (cirDNA) from plasma and cell-surface-bound cirDNA (csb-cirDNA) was shown earlier to be altered in the blood of cancer patients due to accumulation of tumor-specific aberrantly methylated DNA fragments, which are currently considered valuable cancer markers [3, 4]. | |
| 653 | _aонкомаркеры | ||
| 653 | _aрак легкого | ||
| 653 | _aциркулирующая опухолевая ДНК | ||
| 653 | _aметилирование | ||
| 655 | 4 |
_aстатьи в сборниках _9713576 |
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| 700 | 1 |
_aPonomaryova, Anastasia A. _9105492 |
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| 700 | 1 |
_aBondar, Anna A. _9806748 |
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| 700 | 1 |
_aCherdyntseva, Nadezhda V. _996119 |
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| 700 | 1 |
_aZavyalov, A. A. _9279530 |
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| 700 | 1 |
_aTuzikov, Sergey A. _9807147 |
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| 700 | 1 |
_aVlassov, Valentin V. _9279532 |
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| 700 | 1 |
_aLaktionov, Pavel P. _9279534 |
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| 700 | 1 |
_aRykova, Elena Yu. _9279533 |
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| 700 | 1 |
_aDobrodeev, A. Y. _9279529 |
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| 773 | 0 |
_tThe 22nd International Charles Heidelberger symposium on cancer research : proceedings of the International symposium, 17-19 September 2018 _dTomsk, 2018 _gP. 88-89 _z9785751125486 |
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| 852 | 4 | _aRU-ToGU | |
| 856 | 4 | _uhttp://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000662058 | |
| 908 | _aстатья | ||
| 999 | _c459470 | ||