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| 001 | vtls000635385 | ||
| 003 | RU-ToGU | ||
| 005 | 20210922095518.0 | ||
| 007 | cr | | ||
| 008 | 181030s2018 ru fs 100 0 rus d | ||
| 035 | _ato000635385 | ||
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_aRU-ToGU _brus _cRU-ToGU |
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| 100 | 1 |
_aПросекина, Елизавета Андреевна _9482387 |
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| 245 | 1 | 0 |
_aОценка противоопухолевой эффективности различных видов ИПМИ в сочетанном действии с доксорубицином in vitro _cЕ. А. Просекина |
| 246 | 1 | 1 | _aAntitumor therapy efficiency of different types of nanosecond pulseperiodic microwave radiation in combination with doxorubicin in vitro |
| 504 | _aБиблиогр.: 4 назв. | ||
| 520 | 3 | _aIt is known that the action of high-amplitude electric pulses can significantly increase the permeability of cell membranes due to the formation ofpores in them (electroporation). The aim of this research was to study the possibility of forming electropores in membranes of tumor cells by means of a non-invasive method using nanosecond microwave pulses for effective delivery of chemotherapeutic agents to the cell. The HeLa cell line was used as a model object. Doxorubicin was used as a chemotherpeutic drug in various concentrations: 0.5, 1.0 and 2.5 pM. Radiation was carried out on two sources of pulsed-periodic microwave radiation, characterized by different parameters. It was found that, 24 hours after exposure at pulse repetition rates of 13 and 16 Hz in combination with doxorubicin, there was an increase in inhibition of tumor cell proliferation by 30 and 40 %, respectively. | |
| 653 | _aимпульсно-периодическое микроволновое излучение | ||
| 653 | _ain vitro технологии | ||
| 653 | _aдоксорубицин | ||
| 653 | _aоблучение | ||
| 653 | _aклеточная пролиферация | ||
| 653 | _aопухолевые клетки | ||
| 655 | 4 |
_aстатьи в сборниках _9713576 |
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| 773 | 0 |
_tПерспективы развития фундаментальных наук. Т. 4 : сборник научных трудов XV Международной конференции студентов, аспирантов и молодых ученых, 24-27 апреля 2018 г. _dТомск, 2018 _gТ. 4 : Биология и фундаментальная медицина. С. 122-124 _z9785946217279 _z9785946217231 _wto000633041 |
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| 852 | 4 | _aRU-ToGU | |
| 856 | 7 | _uhttp://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000635385 | |
| 908 | _aстатья | ||
| 999 | _c441560 | ||