000 01904nab a2200325 c 4500
001 vtls000634831
003 RU-ToGU
005 20210922095509.0
007 cr |
008 181018|2018 ne s a eng dd
024 7 _a10.1007/s10517-018-4157-z
_2doi
035 _ato000634831
040 _aRU-ToGU
_brus
_cRU-ToGU
245 1 0 _aSubpopulation structure of IFNγ-producing T lymphocytes in patients with pulmonary tuberculosis
_cT. E. Kononova, O. I. Urazova, V. V. Novitskii [et al.]
504 _aБиблиогр.: 9 назв.
520 3 _aThe study of subpopulation structure of IFNγ-producing T cells in patients with pulmonary tuberculosis revealed a decrease in the number of CD3+ IFNγ+ cells against the background of significantly increased IFNγ secretion in vitro irrespective of the clinical form of the disease and drug sensitivity of M. tuberculosis, most strongly expressed in case of the disseminated tuberculosis. In patients with infiltrative drug-sensitive and drug-resistant pulmonary tuberculosis, increased number of Th1/Th17 lymphocytes (CD4+ IFNγ+IL-17A+) and, conversely, decreased number of blood γδT cells was detected.
653 _aЛимфоциты
653 _aтуберкулез легких
655 4 _aстатьи в журналах
_9745982
700 1 _aUrazova, Olga Ivanovna
_9487080
700 1 _aNovitskiy, Vyacheslav Viktorovich
_9106390
700 1 _aEsimova, I. E.
_9487081
700 1 _aChurina, Elena Georgievna
_9487082
700 1 _aKononova, T. E.
_9487083
773 0 _tBulletin of experimental biology and medicine
_d2018
_gVol. 165, № 3. P. 311-314
_x0007-4888
852 4 _aRU-ToGU
856 7 _uhttp://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000634831
908 _aстатья
999 _c441492