| 000 | 03193nab a2200349 c 4500 | ||
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| 001 | vtls000618363 | ||
| 003 | RU-ToGU | ||
| 005 | 20230206170322.0 | ||
| 007 | cr | | ||
| 008 | 171222|2017 xxu s a eng d | ||
| 024 | 7 |
_a10.1117/12.2253023 _2doi |
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| 035 | _ato000618363 | ||
| 040 |
_aRU-ToGU _brus _cRU-ToGU |
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| 245 | 1 | 0 |
_aComparative study of the optical properties of colon mucosa and colon precancerous polyps be tween 400 and 1000 nm _cS. Sónia, N. Gueiral, E. Nogueira [et.al.] |
| 504 | _aБиблиогр.: 35 назв. | ||
| 520 | 3 | _aOptical properties of biological tissues are unique and may be used for tissue identification, tissue discrimination or even to identify pathologies. Early stage colorectal cancer evolves from adenomatous polyps that arise in the inner layer of the colorectal tube — the mucosa. The identification of different optical properties between healthy and pathological colorectal tissues might be used to identify different tissue components and to develop an early stage diagnosis method using optical technologies. Since most of the biomedical optics techniques use light within the visible and near infrared wavelength ranges, we used the inverse adding-doubling method to make a fast estimation of the optical properties of colorectal mucosa and early stage adenocarcinoma between 400 and 1000 nm. The estimated wavelength dependencies have provided information about higher lipid content in healthy mucosa and higher blood content in pathological tissue. Such data has also indicated that the wavelength dependence of the scattering coefficient for healthy mucosa is dominated by Rayleigh scattering and for pathological mucosa it is dominated by Mie scattering. Such difference indicates smaller scatterer size in healthy mucosa tissue. Such information can now be used to develop new diagnosis or treatment methods for early cancer detection or removal. One possibility is to use optical clearing technique to improve tissue transparency and create localized and temporary tissue dehydration for image contrast improvement during diagnosis or polyp laser removal. Such techniques can now be developed based on the different results that we have found for healthy and pathological colorectal mucosa. | |
| 653 | _aслизистая оболочка толстой кишки | ||
| 653 | _aоптические свойства | ||
| 653 | _aполипы | ||
| 655 | 4 |
_aстатьи в журналах _9745982 |
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| 700 | 1 |
_aSónia, Sónia _9478872 |
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| 700 | 1 |
_aNogueira, Elisabete _9478873 |
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| 700 | 1 |
_aHenrique, Rui _9269385 |
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| 700 | 1 |
_aOliveira, Luís Manuel _9855298 |
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| 700 | 1 |
_aTuchin, Valery V. _978712 |
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| 700 | 1 |
_aGueiral, Nuno _9478874 |
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| 773 | 0 |
_tProceedings of SPIE _d2017 _gVol. 10063 : Dynamics and fluctuations in biomedical photonics XIV, 29–30 January 2017, San Francisco, California, United States. P. 100631L-1-100631L-16 _x1996-756X |
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| 852 | 4 | _aRU-ToGU | |
| 856 | 7 | _uhttp://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000618363 | |
| 908 | _aстатья | ||
| 999 | _c428846 | ||