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008 170213s2015 gw | s |||| 0|eng d
020 _a9783662470398
_9978-3-662-47039-8
024 7 _a10.1007/978-3-662-47039-8
_2doi
035 _ato000561866
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aRL1-803
072 7 _aMJK
_2bicssc
072 7 _aMED017000
_2bisacsh
082 0 4 _a616.5
_223
245 1 0 _aPercutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement
_helectronic resource
_bModification of the Stratum Corneum /
_cedited by Nina Dragicevic, Howard I. Maibach.
250 _a1st ed. 2015.
260 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2015.
300 _aXVI, 411 p. 123 illus., 56 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
505 0 _aFrom the contents: THE ROLE OF SKIN HYDRATION IN PENETRATION ENHANCEMENT -- CHEMICAL PENETRATION ENHANCERS IN PENETRATION ENHANCEMENT.-Classification -- Mechanism -- Structure–Activity Relationship -- The Microenvironment Of The Enhancer Site Of Action -- Sulphoxides And Similar Chemicals -- Iminosulfuranes -- Azone  And Azone Analogues -- Fatty Acids, Fatty Acid Esters And Fatty Alcohols -- Alcohols And Glycols -- Terpenes And Essential Oils -- Transcutol Surfactants -- Nonionic Surfactants -- Natural Surfactants Of The Alkylpolyglucoside Type -- Sucrose Esters -- Pyrrolidones -- Chitosan -- Urea And Its Derivatives -- Transcarbams -- Amines And Amides -- Peptides -- Synergistic Effects -- CHEMICAL METHODS FOR TRANSDERMAL DELIVERY OF PEPTIDES AND PROTEINS -- Ultradeformable Vesicles -- Biphasic Vesicles For Transdermal Delivery Of Proteins -- CHEMICAL METHODS IN CUTANEOUS VACCINATION -- Vesicular Carriers In Transcutaneous DNA Vaccination -- Nanoparticles And Microparticles For Transcutaneous DNA Vaccination -- Chitosan-Nanoparticles In Gene Delivery.
520 _aPercutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered and the latest findings are provided on skin structure and function, mathematics in skin permeation and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners and also students.
650 0 _amedicine.
_9566220
650 0 _apharmacology.
_9460043
650 0 _aDermatology.
_9305072
650 1 4 _aMedicine & Public Health.
_9566221
650 2 4 _aDermatology.
_9305072
650 2 4 _aPharmacology/Toxicology.
_9302222
700 1 _aDragicevic, Nina.
_eeditor.
_9470052
700 1 _aMaibach, Howard I.
_eeditor.
_9319235
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-662-47039-8
912 _aZDB-2-SME
999 _c416832