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008 170213s2015 gw | s |||| 0|eng d
020 _a9783662451885
_9978-3-662-45188-5
024 7 _a10.1007/978-3-662-45188-5
_2doi
035 _ato000561612
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aRE1-994
072 7 _aMJQ
_2bicssc
072 7 _aMED063000
_2bisacsh
082 0 4 _a617.7
_223
245 1 0 _aGene- and Cell-Based Treatment Strategies for the Eye
_helectronic resource
_cedited by Elizabeth P. Rakoczy.
260 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2015.
300 _aVII, 95 p. 30 illus., 22 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aEssentials in Ophthalmology,
_x1612-3212
505 0 _aIntroduction -- Gene Therapy for Leber’s Congenital Amaurosis due to RPE65 Mutations -- Gene Therapy for Choroideremia -- Gene Therapy for Dominantly Inherited Retinal Degeneration -- Age-Related Macular Degeneration: The Challenges -- Neovascular Age Related Macular Degeneration: Secretion Gene Therapy -- Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium for the Treatment of Macular Degeneration -- Restoring Physiologic Barriers Against Neovascular Invasion.
520 _aIn this book, leading experts provide detailed descriptions of the exciting treatments that are expected to become part of the ophthalmologist’s arsenal within the next 10–20 years. The treatments discussed relate to a wide variety of conditions, including macular degeneration, Leber’s congenital amaurosis, retinitis pigmentosa and choroideremia. The authors explain clearly how different gene and cell therapies work and provide first-hand accounts of the difficulties that they have faced in bringing these technologies to clinical trial, such as issues relating to funding and ownership. Results achieved to date are presented, and the further steps required before the treatment in question can become a routine option are considered. Gene- and Cell-Based Treatment Strategies for the Eye is unique in showing the organic development of cutting-edge science into potential treatments for eye disease without compromising on accurate reporting of scientific facts. It will persuade the average practitioner or researcher – whether ophthalmologist, health worker, or scientist – that change is indeed coming and is not just a hollow promise of the tabloid media.
650 0 _amedicine.
_9566220
650 0 _aHuman genetics.
_9566248
650 0 _aOphthalmology.
_9566282
650 1 4 _aMedicine & Public Health.
_9566221
650 2 4 _aOphthalmology.
_9566282
650 2 4 _aHuman Genetics.
_9566249
700 1 _aRakoczy, Elizabeth P.
_eeditor.
_9469845
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
830 0 _aEssentials in Ophthalmology,
_9319280
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-662-45188-5
912 _aZDB-2-SME
999 _c416683