000 | 03578nam a22004575i 4500 | ||
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001 | vtls000561452 | ||
003 | RU-ToGU | ||
005 | 20210922090425.0 | ||
007 | cr nn 008mamaa | ||
008 | 170213s2015 gw | s |||| 0|eng d | ||
020 |
_a9783662437339 _9978-3-662-43733-9 |
||
024 | 7 |
_a10.1007/978-3-662-43733-9 _2doi |
|
035 | _ato000561452 | ||
040 |
_aSpringer _cSpringer _dRU-ToGU |
||
050 | 4 | _aRK529-535 | |
072 | 7 |
_aMMDS _2bicssc |
|
072 | 7 |
_aMED085020 _2bisacsh |
|
082 | 0 | 4 |
_a617.522059 _223 |
245 | 1 | 0 |
_aMedication-Related Osteonecrosis of the Jaws _helectronic resource _bBisphosphonates, Denosumab, and New Agents / _cedited by Sven Otto. |
260 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2015. |
||
300 |
_aVIII, 220 p. 83 illus., 63 illus. in color. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
||
337 |
_acomputer _bc _2rdamedia |
||
338 |
_aonline resource _bcr _2rdacarrier |
||
505 | 0 | _aPharmacology of Antiresorptive Drugs -- The Role of Antiresorptive Drugs in the Treatment of Osteoporosis -- The Role of Antiresorptive Drugs in the Treatment of Skeletal Manifestations of Malignant Diseases -- Clinical Features, Localization, Definition and Staging of the Disease -- Radiological Findings / Imaging -- General Characteristics and Risk Factors for BRONJ -- Epidemiology -- Histopathology of BRONJ -- Prevention of Osteonecrosis and Dentoalveolar Surgery Under Treatment With Antiresorptive Drugs -- Bisphosphonates and Dental Implants -- Treatment of BRONJ -- Local and Microvascular Flaps in ONJ-Treatment -- Rehabilitation of Patients After BRONJ -- Adjuvant Treatment Strategies -- Microbiology and Antibiotics -- Animal Models of ONJ -- ONJ Under Denosumab and Other New Drugs -- Possible Use of Antiresorptive Drugs in OMS -- Dental Treatment Under BPs and After BRONJ -- Dental Rehabilitation Under Bisphosphonates and After BRONJ -- History of ONJ. | |
520 | _aOsteonecrosis of the jaws is a well-known side-effect of antiresorptive therapy that predominantly occurs in patients suffering from malignant diseases and receiving intravenous administrations of nitrogen-containing bisphosphonates or subcutaneous administrations of denosumab, a monoclonal antibody. Less frequently it may also be observed in patients with osteoporosis who are being treated with these antiresorptive drugs. This textbook provides detailed, up-to-date information on all aspects of medication-related osteonecrosis of the jaws, including clinical features, pathogenesis, treatment options, and preventive measures. It also explains safe prevention and treatment strategies for patients receiving antiresorptive drugs who require extractions, implant insertions, and other dento-alveolar surgeries. This book will be of major interest for medical and dental students, dentists, and oral and maxillofacial surgeons as well as osteologists and oncologists. | ||
650 | 0 |
_aDentistry. _9310059 |
|
650 | 0 |
_amedicine. _9566220 |
|
650 | 0 |
_aOral surgery. _9460884 |
|
650 | 0 |
_aMaxillofacial surgery. _9460885 |
|
650 | 1 | 4 |
_aMedicine & Public Health. _9566221 |
650 | 2 | 4 |
_aOral and Maxillofacial Surgery. _9315636 |
650 | 2 | 4 |
_aDentistry. _9310059 |
700 | 1 |
_aOtto, Sven. _eeditor. _9468527 |
|
710 | 2 |
_aSpringerLink (Online service) _9143950 |
|
773 | 0 | _tSpringer eBooks | |
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-662-43733-9 |
912 | _aZDB-2-SME | ||
999 | _c415856 |