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008 170212s2015 gw | s |||| 0|eng d
020 _a9783319192130
_9978-3-319-19213-0
024 7 _a10.1007/978-3-319-19213-0
_2doi
035 _ato000560033
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aRC648-665.2
072 7 _aMJG
_2bicssc
072 7 _aMED027000
_2bisacsh
082 0 4 _a616.4
_223
245 1 0 _aThyroid Diseases in Childhood
_helectronic resource
_bRecent Advances from Basic Science to Clinical Practice /
_cedited by Gianni Bona, Filippo De Luca, Alice Monzani.
260 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2015.
300 _aVI, 238 p. 15 illus., 10 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
505 0 _aThyroid embryogenesis -- Thyroid hormones in fetal development -- Etiology of congenital hypothyroidism -- Neonatal screening for congenital hypothyroidism: what it has taught us about thyroid and brain -- Laboratory aspects in neonatal screening of congenital hypothyroidism -- Epidemiology of congenital hypothyroidism -- Congenital hypothyroidism due to PAX8 mutations -- Transient neonatal hypothyroidism -- Central Hypothyroidism -- Syndromes of resistance to thyroid hormone action -- Management of congenital hypothyroidism -- Neurodevelopmental outcomes in children with congenital hypothyroidism -- Iodine deficiency from pregnancy to childhood -- Thyroid enlargement from newborn to adolescent -- Thyroid nodules and carcinoma -- Autoimmune thyroiditis -- Subclinical hypothyroidism -- Hyperthyroidism -- Generation of functional thyroid from embryonic stem cells.
520 _aThis book covers the entire spectrum of thyroid diseases in childhood, focusing on the recent advances that have been achieved, from progress in basic science research through to novel or improved approaches to diagnosis and treatment. Introductory chapters discuss thyroid embryogenesis and the role of thyroid hormones in fetal development. The two contrasting forms of thyroid dysfunction, hypo- and hyperthyroidism, are then considered in depth, with particular attention to the molecular causes of congenital hypothyroidism. Among the other topics addressed are autoimmune thyroiditis, thyroid nodules, and pediatric neoplasms. The book concludes with an overview of promising therapeutic approaches, such as stem cell therapy. Each topic is treated by an eminent expert in the field, ensuring consistently high quality. Thyroid Diseases in Childhood will be an important source of information for endocrinologists, pediatricians, oncologists, and gynecologists, as well as other professionals interested in this topic.
650 0 _amedicine.
_9566220
650 0 _aEndocrinology.
_9303589
650 0 _aOncology.
_9303086
650 0 _aPediatrics.
_9303296
650 1 4 _aMedicine & Public Health.
_9566221
650 2 4 _aEndocrinology.
_9303589
650 2 4 _aPediatrics.
_9303296
650 2 4 _aOncology.
_9303086
700 1 _aBona, Gianni.
_eeditor.
_9466297
700 1 _aDe Luca, Filippo.
_eeditor.
_9466298
700 1 _aMonzani, Alice.
_eeditor.
_9466299
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-19213-0
912 _aZDB-2-SME
999 _c414458