000 04238nam a22004935i 4500
001 vtls000558279
003 RU-ToGU
005 20210922085524.0
007 cr nn 008mamaa
008 170212s2015 gw | s |||| 0|eng d
020 _a9783319125534
_9978-3-319-12553-4
024 7 _a10.1007/978-3-319-12553-4
_2doi
035 _ato000558279
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aRC254-282
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a616.994
_223
245 1 0 _aComparative Effectiveness in Surgical Oncology
_helectronic resource
_bKey Questions and How to Answer Them /
_cedited by Karl Y. Bilimoria, Christina A. Minami, David M. Mahvi.
260 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2015.
300 _aXV, 259 p. 14 illus., 6 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aCancer Treatment and Research,
_x0927-3042 ;
_v164
505 0 _aApproaches to Answering Critical CER Questions -- Leveraging Comparative Effectiveness Research to Improve the Quality of Multidisciplinary Care for Breast Cancer Patients -- Comparative Effectiveness in Melanoma -- Comparative Effectiveness Research for Sarcoma -- Comparative Effectiveness in Thyroid Cancer -- Comparative Effectiveness in Head and Neck Malignancies -- Comparative Effectiveness Issues in Lung Cancer -- Comparative Effectiveness in Esophagogastric Cancer -- Comparative Effectiveness in Colon and Rectal Cancer -- Research Gaps in Pancreatic Cancer Research and Comparative Effectiveness Research Methodologies -- Comparative Effectiveness in Surgical Oncology: Hepatic Malignancies -- Comparative Effectiveness Research in Urologic Cancers -- Comparative Effectiveness Research in Gynecologic Oncology.
520 _aDespite tremendous recent advances in the treatment of most malignancies, there remain several critical questions for each cancer. This particularly true for the surgical management of solid-organ malignancies.  Comparative effectiveness is a relatively new term which encompasses the age-old concepts of how best to treat cancer patients. Comparative effectiveness is defined as the direct comparison of healthcare interventions to determine which work best for which patients when considering the benefits and risks. The Institute of Medicine has defined comparative effectiveness research (CER) as the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care.   CER is certainly best done with well-conducted randomized controlled trials. Unfortunately, clinical trials are not always feasible owing to the impracticality of conducting the trial, the considerable cost, and the time required to complete the trial. These challenges are even more pronounced with respect to surgical treatment.  Thus alternative approaches may need to be considered in order to address pressing questions in the care of the oncology patient. These approaches may include well-conducted retrospective cohort studies from cancer registries and other data sources, decision and cost-effectiveness analyses, and other novel methodologies. This book lays out the current critical questions for each major malignancy and proposes approaches to gain answers to these pressing questions.
650 0 _amedicine.
_9566220
650 0 _aOncology.
_9303086
650 0 _aSurgery.
_9303088
650 1 4 _aMedicine & Public Health.
_9566221
650 2 4 _aOncology.
_9303086
650 2 4 _aSurgery.
_9303088
700 1 _aBilimoria, Karl Y.
_eeditor.
_9463779
700 1 _aMinami, Christina A.
_eeditor.
_9463780
700 1 _aMahvi, David M.
_eeditor.
_9463781
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
830 0 _aCancer Treatment and Research,
_9303313
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-12553-4
912 _aZDB-2-SME
999 _c412889