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008 170212s2015 xxu| s |||| 0|eng d
020 _a9781493928866
_9978-1-4939-2886-6
024 7 _a10.1007/978-1-4939-2886-6
_2doi
035 _ato000557077
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aRB1-214
072 7 _aMMF
_2bicssc
072 7 _aMED067000
_2bisacsh
082 0 4 _a616.07
_223
245 1 0 _aPrecision Molecular Pathology of Breast Cancer
_helectronic resource
_cedited by Ashraf Khan, Ian O. Ellis, Andrew M. Hanby, Ediz F. Cosar, Emad A. Rakha, Dina Kandil.
250 _a1st ed. 2015.
260 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2015.
300 _aX, 338 p. 29 illus., 28 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aMolecular Pathology Library,
_x1935-987X ;
_v10
505 0 _aMolecular basis of breast cancer imaging -- Familial Breast Cancer and Genetic Predisposition in Breast Cancer -- Modelling the Molecular Pathology of Breast Cancer Initiation -- Molecular Pathology of Precancerous Lesions of the Breast -- Breast Cancer Stem Cells: Role in Tumor Initiation, Progression and Targeted Therapy -- Molecular Pathology of Pre-Invasive Ductal Carcinoma. -Molecular Pathology of Lobular Carcinoma Ali Sakhdari, Lloyd Hutchinson, Ediz Cosar -- Molecular Pathology of Hormone Regulation in Breast Cancer: Hormone Receptor Evaluation and Therapeutic Implications -- Molecular Pathology of HER Family of Oncogenes in Breast Cancer: HER-2 Evaluation and Role in Targeted Therapy -- Molecular Classification of Breast Cancer -- Triple Negative Breast Cancer: Subtypes with Clinical Implications -- Molecular-based Diagnostic, Prognostic and Predictive Tests in Breast Cancer -- Role of MicroRNAs in Breast Cancer -- Molecular Pathology of Fibroepithelial Neoplasms of the Breast -- Molecular Features of Mesenchymal Tumors of the Breast -- Molecular Pathology of Breast Cancer Metastasis -- The molecular pathology of chemoresistance during the therapeutic response in breast cancer -- The Molecular Pathology of Male Breast Cancer -- Specimens for Molecular Testing in Breast Cancer.
520 _aThis volume provides a comprehensive review of the molecular mechanisms involved in precancerous lesions and benign and malignant breast tumors. Given the complex molecular pathways in breast cancer biology, the book simplifies these complex mechanisms and highlights the practical issues important for daily practice. Sections are structured to review breast carcinogenesis and the role of familial predisposition and stem cells in initiation and progression of breast cancer. In-depth chapters present morphologic and molecular correlations in precancerous and malignant breast lesions, while outlining highly practical issues that are in practice today in breast pathology, such as evaluation of estrogen, progesterone receptors, and HER-2.   Written by experts in the field, Precision Molecular Pathology of Breast Cancer is a valuable resource that covers the current practice of breast pathology and looks into the future with an emphasis on the molecular basis of breast cancer.
650 0 _amedicine.
_9566220
650 0 _aGynecology.
_9303302
650 0 _aOncology.
_9303086
650 0 _aPathology.
_9303087
650 1 4 _aMedicine & Public Health.
_9566221
650 2 4 _aPathology.
_9303087
650 2 4 _aOncology.
_9303086
650 2 4 _aGynecology.
_9303302
700 1 _aKhan, Ashraf.
_eeditor.
_9461763
700 1 _aEllis, Ian O.
_eeditor.
_9461764
700 1 _aHanby, Andrew M.
_eeditor.
_9461765
700 1 _aCosar, Ediz F.
_eeditor.
_9461766
700 1 _aRakha, Emad A.
_eeditor.
_9461767
700 1 _aKandil, Dina.
_eeditor.
_9461768
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
830 0 _aMolecular Pathology Library,
_9461354
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4939-2886-6
912 _aZDB-2-SME
999 _c411765