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020 _a9781493919352
_9978-1-4939-1935-2
024 7 _a10.1007/978-1-4939-1935-2
_2doi
035 _ato000556921
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI017000
_2bisacsh
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.9453
_223
245 1 0 _aStudies on the Cornea and Lens
_helectronic resource
_cedited by Mark A. Babizhayev, David Wan-Cheng Li, Anne Kasus-Jacobi, Lepša Žorić, Jorge L. Alió.
260 _aNew York, NY :
_bSpringer New York :
_bImprint: Humana Press,
_c2015.
300 _aXVI, 447 p. 124 illus., 81 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aOxidative Stress in Applied Basic Research and Clinical Practice,
_x2197-7224
505 0 _a1 Oxidative Stress in Cornea -- 2 Corneal Degenerations -- 3 Corneal Epithelial Nuclear Ferritin and its Transporter Ferritoid Afford Unique Protection to DNA from U.V. Light and Reactive Oxygen Species -- 4 Excitatory Amino Acid Transporters, Xc- Antiporter, Glutamyl Transpeptidase, Glutamine Synthetase Activity and Glutathione in Human Corneal Epithelial Cells -- 5 Transforming Growth Factor – β3 Regulates Cell Metabolism in Corneal Keratocytes and Fibroblasts -- 6 Corneal Stem Cells: a Source of Cell Renewal with Therapeutic Potential -- 7 New Agents for Treating Dry Eye Syndrome -- 8 Investigating Carcinine Transport and the Expression Profile of Transporter Genes in Human Corneal Epithelial Cells -- 9 Basic Review of the Oxidative Stress Role in Age-Related Cataractogenesis -- 10 The Human Lens: A living Biometric Indicator of Health Status and Successful Aging -- 11 Oxidative Stress in Lens -- 12 Protein Serine/Threonine Phosphatases-1 and –2A in Lens Development and Pathogenesis -- 13 Proteases in Lens and Cataract -- 14 Photosensitized Oxidation of Lens Proteins Exposed to UVA-Visible Light at Low Oxygen Concentration: Its Effect on the Proteasome System -- 15 p53 Regulates Developmental Apoptosis and Gene Expression to Modulate Lens Differentiation -- 16 Etiology and Prevention of Cataract -- 17 The Effects of Lutein in Preventing Cataract Progression -- 18 Antioxidant Defense Network in the Lens and Benefits of Glutathione Prodrugs in Cataracts -- 19 Updates and Advanc es in Corneal Surgery -- 20 Cataract and Diabetic Retinopathy -- 21 Traumatic Cataract-a Review -- 22 Cataract in Paediatric Age Group-a Review.
520 _aThis comprehensive volume presents data describing the role of oxidative stress in anterior eye disease. The content is divided into three logical parts: basic science of the cornea, basic science of the lens, and clinical practices. The first two parts include eighteen chapters that discuss topics ranging from oxidative stress and dry eye disease, endogenous protection of corneal cells against oxidative damage, the therapeutic potential of corneal stem cells, etiology of cataracts and preventive measures, corneal degeneration through oxidative stress and cataract formation, and function and dysregulation of ion channels and transporters in the ocular lens, among others. The concluding part is comprised of four chapters devoted to advancements in corneal surgery, cataract and diabetic retinopathy, the clinical treatment of cataracts including traumatic cataracts, and cataracts in the pediatric age group. Studies on the Cornea and Lens is an essential addition to the library or department of physicians and scientists who treat or research these ocular conditions, particularly cataracts. It is also a key resource for cell biologists studying oxidative stress. This book is an authoritative contribution to Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice series.
650 0 _aLife Sciences.
_9295653
650 0 _aOphthalmology.
_9566282
650 0 _aApoptosis.
_9413673
650 0 _aOxidative Stress.
_9413391
650 1 4 _aLife Sciences.
_9295653
650 2 4 _aOxidative Stress.
_9413391
650 2 4 _aOphthalmology.
_9566282
650 2 4 _aApoptosis.
_9413673
700 1 _aBabizhayev, Mark A.
_eeditor.
_9461656
700 1 _aLi, David Wan-Cheng.
_eeditor.
_9461657
700 1 _aKasus-Jacobi, Anne.
_eeditor.
_9461658
700 1 _aŽorić, Lepša.
_eeditor.
_9461659
700 1 _aAlió, Jorge L.
_eeditor.
_9451840
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
830 0 _aOxidative Stress in Applied Basic Research and Clinical Practice,
_9413393
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4939-1935-2
912 _aZDB-2-SBL
999 _c411704