000 04260nam a22004695i 4500
001 vtls000545722
003 RU-ToGU
005 20210922083348.0
007 cr nn 008mamaa
008 160915s2014 ja | s |||| 0|eng d
020 _a9784431544210
_9978-4-431-54421-0
024 7 _a10.1007/978-4-431-54421-0
_2doi
035 _ato000545722
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aRG1-991
072 7 _aMJT
_2bicssc
072 7 _aMED033000
_2bisacsh
082 0 4 _a618.1
_223
245 1 0 _aEndometriosis
_helectronic resource
_bPathogenesis and Treatment /
_cedited by Tasuku Harada.
260 _aTokyo :
_bSpringer Japan :
_bImprint: Springer,
_c2014.
300 _aIX, 477 p. 69 illus., 44 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
505 0 _aPreface -- PARTⅠ. INTRODUCTION -- Endometriosis: a mysterious disease -- PartⅡ. BASIC SCIENCE -- Pathological aspect and pathogenesis of endometriosis -- Visible and invisible (occult) endometriosis -- Role of stem cells in the pathogenesis of endometriosis -- Role of NK cells in endometriosis -- Macrophages in Pathophysiology of Endometriosis -- Inflammation and Cytokines in Endometriosis -- Epigenetics in endometriosis -- Roles of Prostaglandin E2 in Endometriosis -- Sex steroids and endometriosis -- Aromatase expression in endometriosis and its significance -- Apoptosis in Endometriosis -- Role of nerve fibres in endometriosis -- Endometriosis in experimental models -- Malignant transformation of endometriosis – underlying mechanisms -- Potential new drugs for endometriosis: experimental evidence -- Altered Biological Characteristics of Eutopic and Ectopic Endometrium -- PartⅢ. CLINICAL SCIENCE -- Prevention of Endometriosis -- MR imaging of endometriosis -- Biomarkers of endometriosis -- Classification of Endometriosis -- The Association of Endometriosis with Ovarian Cancer: A Critical Review of Epidemiological Data -- Surgical management of endometriosis -- Systematic laparoscopic surgery of complete obliteration of the cul-de-sac -- Prevention of recurrence after surgery -- Ovarian reserve in patients with endometriosis -- Infertility treatment of endometriosis patients -- Pregnancy complications associated with endometriosis -- Malignant transformation of endometriosis.
520 _aEndometriosis is one of the most common gynecological diseases, causing pelvic pain, infertility, and cancer. The condition reduces the quality of life for the estimated 10% of menstruating women who are affected by it.  This book provides a clear insight into the pathogenesis and pathophysiology of endometriosis—essential information for clinicians intending to successfully treat the condition. The first part covers a range of topics including stem cells, NK cells, macrophages, inflammation, cytokines, epigenetics, prostaglandin, sex steroids, aromatase, apoptosis, nerve fibers, and malignant transformation to aid in understanding the pathogenesis and pathophysiology of the disease. The second part provides useful tools for therapy, specifically, notable recent techniques in prevention, imaging, biomarkers, medical treatments, surgical treatments, prevention of recurrence, and infertility treatments. Each chapter was written by an expert in the field, with nearly 40 researchers and clinicians contributing to the work. This book will be highly useful to clinicians as well as to research scientists who are interested in this enigmatic disease.  .
650 0 _amedicine.
_9566220
650 0 _aGynecology.
_9303302
650 0 _aObstetrics.
_9306262
650 0 _aUrology.
_9308137
650 1 4 _aMedicine & Public Health.
_9566221
650 2 4 _aGynecology.
_9303302
650 2 4 _aUrology/Andrology.
_9308138
650 2 4 _aObstetrics/Perinatology.
_9306263
700 1 _aHarada, Tasuku.
_eeditor.
_9453980
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
856 4 0 _uhttp://dx.doi.org/10.1007/978-4-431-54421-0
912 _aZDB-2-SME
999 _c403320