| 000 | 03539nam a22005295i 4500 | ||
|---|---|---|---|
| 001 | vtls000545486 | ||
| 003 | RU-ToGU | ||
| 005 | 20210922083316.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 160915s2014 gw | s |||| 0|eng d | ||
| 020 |
_a9783662440032 _9978-3-662-44003-2 |
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| 024 | 7 |
_a10.1007/978-3-662-44003-2 _2doi |
|
| 035 | _ato000545486 | ||
| 040 |
_aSpringer _cSpringer _dRU-ToGU |
||
| 050 | 4 | _aRC254-282 | |
| 072 | 7 |
_aMJCL _2bicssc |
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_aMED062000 _2bisacsh |
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_a616.994 _223 |
| 245 | 1 | 0 |
_aRenal Tumors of Childhood _helectronic resource _bBiology and Therapy / _cedited by Kathy Pritchard-Jones, Jeffrey S. Dome. |
| 260 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg : _bImprint: Springer, _c2014. |
||
| 300 |
_aX, 281 p. 80 illus., 55 illus. in color. _bonline resource. |
||
| 336 |
_atext _btxt _2rdacontent |
||
| 337 |
_acomputer _bc _2rdamedia |
||
| 338 |
_aonline resource _bcr _2rdacarrier |
||
| 490 | 1 |
_aPediatric Oncology, _x1613-5318 |
|
| 505 | 0 | _aEpidemiology of Renal Tumours of Childhood -- Genetic Predisposition to Wilms Tumour -- Clinical Presentation -- Pathology -- Treatment of Wilms Tumor in the Children’s Oncology Group -- Treatment of Wilms Tumor – The SIOP approach -- Treatment of Relapsed Wilms Tumor -- Imaging -- Biological prognostic pathways -- Molecular Targeted Therapy for Pediatric Renal Tumors -- Surgical Consideration For Wilms Tumours and other Neoplastic Renal Lesions -- Radiotherapy for Wilms' Tumour and other Childhood Renal Cancers -- Late effects and QOL -- Non-Wilms Pediatrci Renal Tumors -- Wilms Tumor in Low Income Countries. | |
| 520 | _aThis book provides a comprehensive overview of the biological basis of renal tumors in childhood and the clinical approaches to their treatment. Recent advances in our understanding of the molecular genetics of Wilms and other renal tumors are placed in their clinical context, including the differing treatment approaches of immediate surgery or pre-operative chemotherapy. The challenges in applying this knowledge to improve risk stratification and to incorporate biologically targeted agents into front-line therapy are discussed. In addition, the current state of thinking of the two major clinical trial groups in these diseases is presented. All of the authors are experts from Europe and North America, and the book has been written specifically as an easy reference for the practising clinician and the research scientist. It lays the basis for understanding the future direction of clinical and translational research to improve outcomes in patients with childhood renal tumors and will prove indispensable for those treating or researching into these diseases. | ||
| 650 | 0 |
_amedicine. _9566220 |
|
| 650 | 0 |
_aOncology. _9303086 |
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| 650 | 0 |
_aCancer _xSurgery. _9303085 |
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| 650 | 0 |
_aPathology. _9303087 |
|
| 650 | 0 |
_aPediatrics. _9303296 |
|
| 650 | 1 | 4 |
_aMedicine & Public Health. _9566221 |
| 650 | 2 | 4 |
_aOncology. _9303086 |
| 650 | 2 | 4 |
_aSurgical Oncology. _9303089 |
| 650 | 2 | 4 |
_aPediatrics. _9303296 |
| 650 | 2 | 4 |
_aPathology. _9303087 |
| 700 | 1 |
_aPritchard-Jones, Kathy. _eeditor. _9453682 |
|
| 700 | 1 |
_aDome, Jeffrey S. _eeditor. _9453683 |
|
| 710 | 2 |
_aSpringerLink (Online service) _9143950 |
|
| 773 | 0 | _tSpringer eBooks | |
| 830 | 0 |
_aPediatric Oncology, _9316285 |
|
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-662-44003-2 |
| 912 | _aZDB-2-SME | ||
| 999 | _c403149 | ||