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020 _a9783642410277
_9978-3-642-41027-7
024 7 _a10.1007/978-3-642-41027-7
_2doi
035 _ato000544796
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aSB123-123.5
050 4 _aS494.5.B563
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_2bicssc
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_2bisacsh
072 7 _aSCI01000
_2bisacsh
082 0 4 _a631.52
_223
082 0 4 _a660.6
_223
245 1 0 _aArtemisia annua - Pharmacology and Biotechnology
_helectronic resource
_cedited by Tariq Aftab, Jorge F.S. Ferreira, M. Masroor A. Khan, M. Naeem.
260 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2014.
300 _aVI, 292 p. 50 illus., 21 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
505 0 _aHow a herbal drug application interrelates with its therapeutic effects: reflections on qinghao青蒿 (Artemisia annua, L.) in the Chinese materia medica -- Ethno-pharmacology of Artemisia annua: A review -- Artemisia annua: a miraculous herb to cure malaria -- The whole-plant approach to therapeutic use of Artemisia annua L. (Asteraceae) -- Pharmacological potentials of artemisinin and related sesquiterpene lactones: recent advances and trends -- Taxonomic implications of Artemisia annua L. (Asteraceae) -- Trichomes in  Artemisia annua: initiation, development, maturation and the possibility to influence these factors -- Potential methods to improve the efficiency of artemisinin extraction from Artemisia annua -- Extraction, purification and quantification of artemisinin and its analogs from Artemisia annua L -- Effect of mineral nutrition, growth regulators and environmental stresses on biomass production and artemisinin concentration of Artemisia annua -- Recent Advances to Enhance Yield of Artemisinin - A Novel Antimalarial Compound, in Artemisia annua L. Plants -- Artemisinin in cancer therapy -- Recent Developments in Controlling Insect, Acari, Nematode and Plant Pathogens of Agricultural and Medical Importance by Artemisia annua L. (Asteraceae) -- Reverse pharmacology and drug discovery: Artemisia annua and its anti-HIV activity.
520 _aThis book summarizes global research on the medicinal plant Artemisia annua and its component artemisinin, an antimalarial agent. It explores further artemisinin applications and future research possibilities. Artemisinin is an effective antimalarial agent, particularly for multi-drug-resistant and cerebral malaria. As the chemical synthesis of artemisinin is complicated and not economically feasible in view of the poor yield of the drug, the intact plant remains the only viable source for artemisinin production. Therefore, it is necessary to increase the concentration of artemisinin in A. annua to reduce the costs of artemisinin-based drugs. Plant scientists have focused their efforts on A. annua to achieve a higher artemisinin crop yield and summarize their findings in this book.
650 0 _aLife Sciences.
_9295653
650 0 _aToxicology.
_9302218
650 0 _aBiochemistry.
_9299060
650 0 _aPlant breeding.
_9304136
650 1 4 _aLife Sciences.
_9295653
650 2 4 _aPlant Breeding/Biotechnology.
_9316059
650 2 4 _aPharmacology/Toxicology.
_9302222
650 2 4 _aPlant Biochemistry.
_9299062
700 1 _aAftab, Tariq.
_eeditor.
_9452831
700 1 _aFerreira, Jorge F.S.
_eeditor.
_9452832
700 1 _aKhan, M. Masroor A.
_eeditor.
_9452833
700 1 _aNaeem, M.
_eeditor.
_9452834
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-41027-7
912 _aZDB-2-SBL
999 _c402654