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008 160915s2014 gw | s |||| 0|eng d
020 _a9783642418570
_9978-3-642-41857-0
024 7 _a10.1007/978-3-642-41857-0
_2doi
035 _ato000544857
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aR1
072 7 _aMB
_2bicssc
072 7 _aMED000000
_2bisacsh
082 0 4 _a610
_223
100 1 _aChiappelli, Francesco.
_eauthor.
_9452415
245 1 0 _aFundamentals of Evidence-Based Health Care and Translational Science
_helectronic resource
_cby Francesco Chiappelli.
260 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2014.
300 _aXXVII, 394 p. 57 illus., 29 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
505 0 _aFundamental Implications for Clinical Practice: Translational Effectiveness in the Context of Translational Science -- Comparative Effectiveness Analysis and Evidence-Based Decisions -- The Best Available Evidence -- Sampling and Assessment of the Evidence -- Systematic Evaluation of Statistical Analysis: Data Analysis in Research Synthesis -- Optimizing Clinical Practice-Based Patient-Centered Outcomes Research: Getting and Understanding Data -- Obtaining Data -- Describing and Analyzing Data -- Translational Effectiveness Analysis -- Optimizing Clinical Outcomes by Individualizing Observations -- Evaluation in Patient-Centered Outcomes Research -- Translational Effectiveness in Practice-Based Patient-Centered Outcomes Research.   .
520 _aComparative effectiveness research – the conduct and synthesis of systematic research in order to compare the benefits and harms of alternative treatment options – is of critical importance in enabling informed health care decisions to be made. This user-friendly, practical handbook examines in depth how best to perform such comparative effectiveness research. A wide range of topics and methods are discussed, including research synthesis, sampling analysis, assessment of evidence design, systematic evaluation of statistical analysis, and meta-analysis. The discussion extends well beyond the fundamentals by encompassing “complex” systematic reviews, “cumulative” meta-analyses, and logic-based versus utility-based decision making. Health care providers, researchers, instructors, and students will all find this to be an invaluable reference on the compelling current issues and important analytical tools in comparative effectiveness research.
650 0 _amedicine.
_9566220
650 1 4 _aMedicine & Public Health.
_9566221
650 2 4 _aMedicine/Public Health, general.
_9265983
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-642-41857-0
912 _aZDB-2-SME
999 _c402416