000 03868nam a22005175i 4500
001 vtls000544038
003 RU-ToGU
005 20210922082933.0
007 cr nn 008mamaa
008 160915s2014 gw | s |||| 0|eng d
020 _a9783319111551
_9978-3-319-11155-1
024 7 _a10.1007/978-3-319-11155-1
_2doi
035 _ato000544038
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aQR355-502
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9101
_223
245 1 0 _aInfluenza Pathogenesis and Control - Volume I
_helectronic resource
_cedited by Richard W. Compans, Michael B. A. Oldstone.
260 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2014.
300 _aVIII, 444 p. 48 illus., 42 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v385
505 0 _aThe Hemagglutinin - a Determinant of Pathogenicity -- Molecular determinants of pathogenicity in the polymerase complex -- Receptor binding properties of the influenza virus hemagglutinin as a determinant of host range -- Acid-induced membrane fusion by the hemagglutinin protein and its role in influenza virus biology -- Pandemic Preparedness and the Influenza Risk Assessment Tool (IRAT) -- Avian influenza virus transmission to mammals -- Transmission in the Guinea Pig Model -- Enhancement of influenza virus transmission by gene reassortment -- Swine and Influenza: A Challenge to One Health Research -- Influenza Pathobiology and Pathogenesis in Avian Species -- Molecular determinants of influenza virus pathogenesis in mice -- Mammalian models for the study of H7 virus pathogenesis and transmission -- Pathogenesis and vaccination of influenza A virus in swine -- Secondary Bacterial Infections in Influenza Virus Infection Pathogenesis -- Evolution and Ecology of Influenza A viruses -- Influenza A virus reassortment -- Antigenic Analyses of Highly Pathogenic Avian Influenza A Viruses.
520 _aThis two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.  .
650 0 _amedicine.
_9566220
650 0 _aImmunology.
_9303380
650 0 _aMedical virology.
_9303541
650 0 _aEmerging infectious diseases.
_9303699
650 1 4 _aBiomedicine.
_9566246
650 2 4 _aVirology.
_9303545
650 2 4 _aImmunology.
_9303380
650 2 4 _aInfectious Diseases.
_9303700
650 2 4 _aHealth Promotion and Disease Prevention.
_9303017
700 1 _aCompans, Richard W.
_eeditor.
_9318969
700 1 _aOldstone, Michael B. A.
_eeditor.
_9323758
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
830 0 _aCurrent Topics in Microbiology and Immunology,
_9317060
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-11155-1
912 _aZDB-2-SBL
999 _c401951