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020 _a9783319066837
_9978-3-319-06683-7
024 7 _a10.1007/978-3-319-06683-7
_2doi
035 _ato000543319
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aRM1-950
072 7 _aMMG
_2bicssc
072 7 _aMED071000
_2bisacsh
082 0 4 _a615
_223
245 1 0 _aRecent Developments in the Regulation of Kinins
_helectronic resource
_cedited by Jagdish N. Sharma.
260 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2014.
300 _aIX, 198 p. 17 illus., 7 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aProgress in Drug Research ;
_v69
505 0 _aBasic and clinical aspects of bradykinin receptor antagonists -- The kallikrein-kinin pathways in hypertension and diabetes -- Tissue Kallikrein-kinin therapy in hypertension and organ damage -- Renal (tissue) kallikrein-kinin system in the kidney and novel potential drugs for salt-sensitive hypertension -- The Kallikrein-kinin system in diabetic retinopathy -- Genetic manipulation and genetic variation of the Kallikrein Kinin System; impact on cardiovascular and renal diseases.
520 _aThis volume presents key topics of current interest with regard to several pathophysiological conditions including (a) the basic and clinical aspects of bradykinin receptor antagonists, (b) the kallikrein-kinin pathways in hypertension and diabetes, (c) tissue kallikrein-kinin therapy for hypertension and organ damage, (d) the renal (tissue) kallikrein-kinin system in the kidney and novel potential drugs for salt-sensitive hypertension, (e) the kallikrein-kinin system in diabetes retinopathy, and (f) genetic manipulation and genetic variation of the kallikrein-kinin system and their impacts on cardiovascular and renal disease. Written by internationally reputed scientists, the book provides an essential overview of the latest developments in the field of kinin research, making it a valuable asset for endocrinologists, nephrologists, cardiologists, pharmacologists, physiologists, ophthalmologists and rheumatologists. Furthermore, it is also intended for postgraduate students in the fields of medicine, pharmacy, physiology and pharmacology, and those working at research organizations.
650 0 _amedicine.
_9566220
650 0 _aHuman physiology.
_9566252
650 0 _aToxicology.
_9302218
650 0 _aEndocrinology.
_9303589
650 1 4 _aBiomedicine.
_9566246
650 2 4 _aPharmacology/Toxicology.
_9302222
650 2 4 _aHuman Physiology.
_9566254
650 2 4 _aEndocrinology.
_9303589
700 1 _aSharma, Jagdish N.
_eeditor.
_9450387
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
830 0 _aProgress in Drug Research ;
_9330489
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-319-06683-7
912 _aZDB-2-SBL
999 _c401295