| 000 | 03158nam a22004695i 4500 | ||
|---|---|---|---|
| 001 | vtls000541644 | ||
| 003 | RU-ToGU | ||
| 005 | 20210922082310.0 | ||
| 007 | cr nn 008mamaa | ||
| 008 | 160915s2014 xxu| s |||| 0|eng d | ||
| 020 |
_a9781493911127 _9978-1-4939-1112-7 |
||
| 024 | 7 |
_a10.1007/978-1-4939-1112-7 _2doi |
|
| 035 | _ato000541644 | ||
| 040 |
_aSpringer _cSpringer _dRU-ToGU |
||
| 050 | 4 | _aRC648-665.2 | |
| 072 | 7 |
_aMJG _2bicssc |
|
| 072 | 7 |
_aMED027000 _2bisacsh |
|
| 082 | 0 | 4 |
_a616.4 _223 |
| 245 | 1 | 0 |
_aCholesterol Transporters of the START Domain Protein Family in Health and Disease _helectronic resource _bSTART Proteins - Structure and Function / _cedited by Barbara J. Clark, Douglas M. Stocco. |
| 260 |
_aNew York, NY : _bSpringer New York : _bImprint: Springer, _c2014. |
||
| 300 |
_aXIV, 190 p. 25 illus., 21 illus. in color. _bonline resource. |
||
| 336 |
_atext _btxt _2rdacontent |
||
| 337 |
_acomputer _bc _2rdamedia |
||
| 338 |
_aonline resource _bcr _2rdacarrier |
||
| 505 | 0 | _aAn Introduction to the Steroidogenic Acute Regulatory Protein (StAR)-related Lipid Transfer Domain Protein Family -- The Steroidogenic Acute Regulatory Protein (StAR) -- START domain protein structure and ligand specificity -- Congenital Lipoid Adrenal Hyperplasia -- Steroidogenic Acute Regulatory protein (StAR) and Atherogenesis -- STARD3: a lipid transfer protein in breast cancer and cholesterol trafficking -- The STARD4 subfamily: STARD4 and STARD5 in cholesterol metabolism -- START proteins in non-vesicular cholesterol transport -- Index. | |
| 520 | _aNon-vesicular intracellular cholesterol transport is an important mechanism for maintaining membrane cholesterol homeostasis. Recent reports of studies directed at soluble cholesterol transport proteins indicate that aberrant expression of the START proteins may contribute to disease states associated with disorders in cholesterol homeostasis. This is an exciting new direction in the field and the purpose of this book will be to highlight the current research directed at potential roles for the START family in diabetes, cancer, and atherogenesis. This book also provides a personal and historical perspective of the discovery-to-publication journey that the authors had for their particular START domain family member. The goal will be to provide perspectives to graduate students, post-doctoral fellows, and endocrinology fellows on the research discovery process. | ||
| 650 | 0 |
_amedicine. _9566220 |
|
| 650 | 0 |
_aEndocrinology. _9303589 |
|
| 650 | 0 |
_aBiochemistry. _9299060 |
|
| 650 | 1 | 4 |
_aMedicine & Public Health. _9566221 |
| 650 | 2 | 4 |
_aEndocrinology. _9303589 |
| 650 | 2 | 4 |
_aProtein Science. _9410551 |
| 650 | 2 | 4 |
_aBiomedicine general. _9566281 |
| 700 | 1 |
_aClark, Barbara J. _eeditor. _9448024 |
|
| 700 | 1 |
_aStocco, Douglas M. _eeditor. _9448025 |
|
| 710 | 2 |
_aSpringerLink (Online service) _9143950 |
|
| 773 | 0 | _tSpringer eBooks | |
| 856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-1-4939-1112-7 |
| 912 | _aZDB-2-SBL | ||
| 999 | _c399929 | ||