000 02665nam a22004935i 4500
001 vtls000541099
003 RU-ToGU
005 20210922082057.0
007 cr nn 008mamaa
008 160915s2014 xxu| s |||| 0|eng d
020 _a9781461488095
_9978-1-4614-8809-5
024 7 _a10.1007/978-1-4614-8809-5
_2doi
035 _ato000541099
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
245 1 0 _aAdvances in Tumor Immunology and Immunotherapy
_helectronic resource
_cedited by Joseph D. Rosenblatt, Eckhard R. Podack, Glen N. Barber, Augusto Ochoa.
260 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2014.
300 _aIX, 371 p. 35 illus., 29 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aCurrent Cancer Research
520 _aThis volume explores recent advances in understanding of fundamental immunology  and insights into  the dynamic interactions between tumors and the immune system, that  provide new opportunities  for therapeutic  intervention in cancer.  Chapter topics include evolving paradigms in the innate and adaptive response,   newly appreciated immunosuppressive mechanisms,  and  novel preclinical  strategies for manipulation of the immune system for therapeutic benefit in cancer. In addition, recent successes in the clinic, and emerging opportunities are covered. Future possibilities, such as the use of antibody engineering, fusion proteins,  and the retargeting of immune cells through T-cell receptor engineering are discussed by  leaders in the field,  focusing  on recent clinical experience, promising technologies, and challenges to clinical success.
650 0 _amedicine.
_9566220
650 0 _aOncology.
_9303086
650 0 _aToxicology.
_9302218
650 1 4 _aBiomedicine.
_9566246
650 2 4 _aCancer Research.
_9566267
650 2 4 _aPharmacology/Toxicology.
_9302222
700 1 _aRosenblatt, Joseph D.
_eeditor.
_9446760
700 1 _aPodack, Eckhard R.
_eeditor.
_9446761
700 1 _aBarber, Glen N.
_eeditor.
_9446762
700 1 _aOchoa, Augusto.
_eeditor.
_9446763
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
830 0 _aCurrent Cancer Research
_9446764
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-8809-5
912 _aZDB-2-SME
999 _c399237