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020 _a9781493904976
_9978-1-4939-0497-6
024 7 _a10.1007/978-1-4939-0497-6
_2doi
035 _ato000541499
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI017000
_2bisacsh
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.9453
_223
245 1 0 _aStudies on Respiratory Disorders
_helectronic resource
_cedited by Nirmal K. Ganguly, Surinder K. Jindal, Shyam Biswal, Peter J. Barnes, Ruby Pawankar.
260 _aNew York, NY :
_bSpringer New York :
_bImprint: Humana Press,
_c2014.
300 _aXII, 394 p. 26 illus., 19 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aOxidative Stress in Applied Basic Research and Clinical Practice,
_x2197-7224
505 0 _aIntroduction to oxidative stress and anti-oxidant therapy -- Role of reactive oxygen and nitrogen species in respiratory diseases: general considerations -- Role of exhaled biomarkers volatiles and exhaled breath condensate -- Pulmonary infections and oxidative injury -- Role of reactive oxygen species in causing acute lung injury -- Free radicals in pulmonary tuberculosis -- Oxidative injury caused by smoking and air-pollution -- Oxidative stress in chronic obstructive pulmonary disease -- Oxidative stress in asthma and allergic disease -- Oxygen free radicals in pulmonary hypertension -- Pulmonary fibrosis and oxidative stress -- Oxidant injury in sarcoidosis and other granulomatous disorders -- Oxidative stress in lung cancer -- Pulmonary toxicity from drugs, heavy metals and other poisonings – oxidant injury and role of anti-oxidants -- Oxidative stress and respiratory muscle dysfunction -- The critical role of Nrf2 -- Development of novel antioxidants -- Asbestosis.
520 _aStudies on Respiratory Disorders considers the whole panorama of oxidative damage in different respiratory disorders for the review of clinician and laboratory investigators and makes diverse information available in a single volume.  This volume provides a comprehensive review of numerous studies on the role of oxygen and nitrogen species in lung diseases; it also discusses the potential role of anti-oxidants in their treatment.  The contents are organized into three sections along fairly broad classifications: I.  General introductory chapters on oxidant stress; general considerations related to reactive oxygen and nitrogen species; the role of exhaled breath condensate and other volatile compounds as exhaled biomarkers of inflammation;  II. Oxidative stress in different groups of respiratory disorders such as pulmonary infections (viral, bacterial and tuberculosis);  airway diseases such as chronic obstructive pulmonary diseases, air pollution, allergies and asthma; miscellaneous lung diseases (e.g., interstitial diseases, sarcoidosis, asbestosis, respiratory muscle dysfunction, pulmonary hypertension and cancer); and III., Anti-oxidant drugs. These final chapters on anti-oxidant drugs including the mimics (such as traditional herbs) provide a critical review of the available information on their success and failure.  Studies on Respiratory Disorders is an important addition to the Oxidative Stress in Applied Basic Research and Clinical Practice series and is essential reading  for those treating or researching treatment for respiratory disorders.
650 0 _aLife Sciences.
_9295653
650 0 _aPneumology.
_9304224
650 0 _aCytology.
_9269442
650 1 4 _aLife Sciences.
_9295653
650 2 4 _aOxidative Stress.
_9413391
650 2 4 _aCell Biology.
_9302220
650 2 4 _aPneumology/Respiratory System.
_9304226
700 1 _aGanguly, Nirmal K.
_eeditor.
_9446688
700 1 _aJindal, Surinder K.
_eeditor.
_9446689
700 1 _aBiswal, Shyam.
_eeditor.
_9446690
700 1 _aBarnes, Peter J.
_eeditor.
_9446691
700 1 _aPawankar, Ruby.
_eeditor.
_9332610
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
830 0 _aOxidative Stress in Applied Basic Research and Clinical Practice,
_9413393
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4939-0497-6
912 _aZDB-2-SBL
999 _c399204