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001 vtls000541476
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007 cr nn 008mamaa
008 160915s2014 xxu| s |||| 0|eng d
020 _a9781493903986
_9978-1-4939-0398-6
024 7 _a10.1007/978-1-4939-0398-6
_2doi
035 _ato000541476
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aQP34-38
072 7 _aMFG
_2bicssc
072 7 _aMED075000
_2bisacsh
082 0 4 _a612
_223
245 1 4 _aThe Multiple Therapeutic Targets of A20
_helectronic resource
_cedited by Christiane Ferran.
260 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2014.
300 _aXXI, 188 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598
505 0 _aA20—A Bipartite Ubiquitin Editing Enzyme with Immunoregulatory Potential -- The Biology of A20-Binding Inhibitors of NF- κB Activation (Abins) -- The Biology of A20-Like Molecules -- Anti-Viral Tetris: Modulation of the Innate Anti-Viral Immune Response by A20 -- A20 Expressing Tumors and Anticancer Drug Resistance -- Translational Studies of A20 in Atherosclerosis and Cardiovascular Disease -- A Biomarker of Allograft Outcome: A Showcase in Kidney Transplantation -- A20—An Omnipotent Protein in the Liver: Prometheus Myth Resolved? -- Emerging Roles for A20 in Islet Biology and Pathology -- Single Nucleotide Polymorphisms at the TNFAIP3/A20 Locus and Susceptibility/Resistance to Inflammatory and Autoimmune Diseases.
520 _aThis book is meant to provide the most current knowledge regarding the mechanisms of action of A20, if its versatile functions and their validation in animal models of human disease and its promise as a diagnostic biomarker and therapeutic target.
650 0 _amedicine.
_9566220
650 0 _aHuman physiology.
_9566252
650 0 _aBiochemistry.
_9299060
650 1 4 _aBiomedicine.
_9566246
650 2 4 _aHuman Physiology.
_9566254
650 2 4 _aMedicine/Public Health, general.
_9265983
650 2 4 _aBiochemistry, general.
_9566263
700 1 _aFerran, Christiane.
_eeditor.
_9446150
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
830 0 _aAdvances in Experimental Medicine and Biology,
_9303385
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4939-0398-6
912 _aZDB-2-SBL
999 _c398866