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020 |
_a9781447163800 _9978-1-4471-6380-0 |
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024 | 7 |
_a10.1007/978-1-4471-6380-0 _2doi |
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035 | _ato000540691 | ||
040 |
_aSpringer _cSpringer _dRU-ToGU |
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_aMJN _2bicssc |
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_aMED056000 _2bisacsh |
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_a616.8 _223 |
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_aNeurodegenerative Diseases _helectronic resource _bClinical Aspects, Molecular Genetics and Biomarkers / _cedited by Daniela Galimberti, Elio Scarpini. |
260 |
_aLondon : _bSpringer London : _bImprint: Springer, _c2014. |
||
300 |
_aXIX, 253 p. 15 illus., 9 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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505 | 0 | _aGenetics and Epigenetics: Basic Concepts -- Alzheimer’s Disease: Clinical Aspects and Treatments -- Autosomal Dominant Alzheimer’s Disease: Underlying Causes -- Genetic Risk Factors for Alzheimer’s Disease -- The Role of Cerebrovascular Disease in Cognitive Disease -- Non-genetic Risk Factors for Alzheimer’s disease -- Frontotemporal Lobar Degeneration: Genetics and Clinical Phenotypes -- Alzheimer’s Disease and Frontotemporal Lobar Degeneration: Mouse Models -- Cerebrospinal Fluid Biomarkers in Alzheimer’s Disease and Frontotemporal Dementia -- Biomarkers for Alzheimer’s Disease and Frontotemporal Lobar Degeneration: Imaging -- Amyotrophic Lateral Sclerosis: Genotypes and Phenotypes -- Uncommon Dementias -- Neurodevelopment Alterations, Neurodegeneration and Immunoinflammatory Patterns in the Pathophysiology of Schizophrenia -- Neurodegeneration and Multiple Sclerosis. | |
520 | _aThis book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer’s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments, basic discoveries (genetics and molecular biology), and translation of basic research into biomarkers for early diagnosis. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis. Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields. | ||
650 | 0 |
_amedicine. _9566220 |
|
650 | 0 |
_aHuman genetics. _9566248 |
|
650 | 0 |
_aNeurosciences. _9302217 |
|
650 | 0 |
_aNeurology. _9303067 |
|
650 | 1 | 4 |
_aMedicine & Public Health. _9566221 |
650 | 2 | 4 |
_aNeurology. _9303067 |
650 | 2 | 4 |
_aNeurosciences. _9302217 |
650 | 2 | 4 |
_aHuman Genetics. _9566249 |
700 | 1 |
_aGalimberti, Daniela. _eeditor. _9444823 |
|
700 | 1 |
_aScarpini, Elio. _eeditor. _9444824 |
|
710 | 2 |
_aSpringerLink (Online service) _9143950 |
|
773 | 0 | _tSpringer eBooks | |
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-1-4471-6380-0 |
912 | _aZDB-2-SME | ||
999 | _c398023 |