| 000 | 03297nab a2200373 c 4500 | ||
|---|---|---|---|
| 001 | vtls000578172 | ||
| 003 | RU-ToGU | ||
| 005 | 20221223143616.0 | ||
| 007 | cr | | ||
| 008 | 170623|2015 sz s a eng dd | ||
| 024 | 7 |
_a10.1159/000433554 _2doi |
|
| 035 | _ato000578172 | ||
| 040 |
_aRU-ToGU _brus _cRU-ToGU |
||
| 245 | 1 | 0 |
_aVestibular implants: 8 years of experience with electrical stimulation of the vestibular nerve in 11 patients with bilateral vestibular loss _cN. Guinand, R. van de Berg, S. Cavuscens [et.al.] |
| 504 | _aБиблиогр.: 68 назв. | ||
| 520 | 3 | _aBACKGROUND:The concept of the vestibular implant is primarily to artificially restore the vestibular function in patients with a bilateral vestibular loss (BVL) by providing the central nervous system with motion information using electrical stimulation of the vestibular nerve. Our group initiated human trials about 10 years ago. METHODS: Between 2007 and 2013, 11 patients with a BVL received a vestibular implant prototype providing electrodes to stimulate the ampullary branches of the vestibular nerve. Eye movements were recorded and analyzed to assess the effects of the electrical stimulation. Perception induced by electrical stimulation was documented. RESULTS: Smooth, controlled eye movements were obtained in all patients showing that electrical stimulation successfully activated the vestibulo-ocular pathway. However, both the electrical dynamic range and the amplitude of the eye movements were variable from patient to patient. The axis of the response was consistent with the stimulated nerve branch in 17 out of the 24 tested electrodes. Furthermore, in at least 1 case, the elicited eye movements showed characteristics similar to those of compensatory eye movements observed during natural activities such as walking. Finally, diverse percepts were reported upon electrical stimulation (i.e., rotatory sensations, sound, tickling or pressure) with intensity increasing as the stimulation current increased. CONCLUSIONS: These results demonstrate that electrical stimulation is a safe and effective means to activate the vestibular system, even in a heterogeneous patient population with very different etiologies and disease durations. Successful tuning of this information could turn this vestibular implant prototype into a successful artificial balance organ. | |
| 653 | _aвестибулоокулярный рефлекс | ||
| 653 | _aвестибулярные импланты | ||
| 655 | 4 |
_aстатьи в журналах _9681159 |
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| 700 | 1 |
_aGuinand, Nils _9363292 |
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| 700 | 1 |
_aCavuscens, Samuel _9363287 |
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| 700 | 1 |
_aStokroos, Robert J. _9441870 |
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| 700 | 1 |
_aRanieri, Maurizio _9363286 |
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| 700 | 1 |
_aPelizzone, Marco _9441871 |
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| 700 | 1 |
_aKingma, Herman _9363290 |
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| 700 | 1 |
_aGuyot, Jean-Philippe _9363288 |
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| 700 | 1 |
_aPerez Fornos, Angelica _9363291 |
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| 700 | 1 |
_avan de Berg, Raymond _9363284 |
|
| 773 | 0 |
_tORL _d2015 _gVol. 77, № 4. P. 227-240 _x0301-1569 |
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| 852 | 4 | _aRU-ToGU | |
| 856 | 7 | _uhttp://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000578172 | |
| 908 | _aстатья | ||
| 999 | _c392843 | ||