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008 140715s2013 xxu| s |||| 0|eng d
020 _a9781461477297
_9978-1-4614-7729-7
024 7 _a10.1007/978-1-4614-7729-7
_2doi
035 _ato000483904
040 _aSpringer
_cSpringer
_dRU-ToGU
050 4 _aQR355-502
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9101
_223
100 1 _aFreed, Eric O.
_eeditor.
_9413998
245 1 0 _aAdvances in HIV-1 Assembly and Release
_helectronic resource
_cedited by Eric O. Freed.
260 _aNew York, NY :
_bSpringer New York :
_bImprint: Springer,
_c2013.
300 _aX, 221 p. 36 illus., 31 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
505 0 _aStructural Biology of HIV Assembly -- Cellular Trafficking Mechanisms in the Assembly and Release of HIV -- Packaging of the HIV-1 RNA Genome -- Synthesis of Functional and Variable HIV-1 Envelope Glycoproteins -- HIV-1 Budding -- HIV-1 Maturation -- Cell-to-Cell Transmission of HIV -- Virus Assembly as a Target for Antiretroviral Therapy.
520 _aOver the past decade, enormous progress has been made in understanding the late events in the HIV replication cycle.  This has been made possible by major advances in cell biology, virology, and structural biology.  The field continues to move forward rapidly, with important new discoveries being reported on a regular basis.  The impact of this progress across a broad spectrum of biomedical research has been substantial.  The increase in basic knowledge in the areas of HIV assembly, release, and maturation has been accompanied by new possibilities for therapeutic intervention.The work includes topics relating to basic molecular biology, cell biology, and structural biology of HIV assembly, coupled with more applied ideas of how this basic information can inform the field of antiretroviral research.  The book covers all major topics pertaining to the late stages of HIV replication, with leaders in each area recruited to contribute chapters in their areas of expertise . The topics will be sufficiently focused to allow authors the opportunity to cover the latest developments in detail.
650 0 _amedicine.
_9566220
650 0 _aImmunology.
_9303380
650 0 _amicrobiology.
_9566253
650 0 _aMedical virology.
_9303541
650 1 4 _aBiomedicine.
_9566246
650 2 4 _aVirology.
_9303545
650 2 4 _aImmunology.
_9303380
650 2 4 _aMedical Microbiology.
_9303382
650 2 4 _aMedicine/Public Health, general.
_9265983
710 2 _aSpringerLink (Online service)
_9143950
773 0 _tSpringer eBooks
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-4614-7729-7
912 _aZDB-2-SBL
999 _c356460