TY  - GEN
AU  - Ponomaryova,Anastasia A.
AU  - Bondar,Anna A.
AU  - Cherdyntseva,Nadezhda V.
AU  - Zavyalov,A.A.
AU  - Tuzikov,Sergey A.
AU  - Vlassov,Valentin V.
AU  - Laktionov,Pavel P.
AU  - Rykova,Elena Yu
AU  - Dobrodeev,A.Y.
TI  - Circulating DNA-markers in lung cancer: changes in retrotrasposons methylation status in response therapy and during the post-treatment follow-up
KW  - онкомаркеры
KW  - рак легкого
KW  - циркулирующая опухолевая ДНК
KW  - метилирование
KW  - статьи в сборниках
N1  - Библиогр.: 4 назв
N2  - Malignant cell transformation is accompanied by two processes of DNA methylation changes:
hypermethylation in CpG islands of tumor suppressor genes and global hypomethylation in repetitive
 DNA sequences (retrotransposons) [1, 2]. The composition of circulating DNA (cirDNA) from
 plasma and cell-surface-bound cirDNA (csb-cirDNA) was shown earlier to be altered in the blood
 of cancer patients due to accumulation of tumor-specific aberrantly methylated DNA fragments,
 which are currently considered valuable cancer markers [3, 4]
UR  - http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000662058
ER  -