TY  - GEN
AU  - Gomboeva,S.B.
AU  - Ryabov,Vyacheslav V.
AU  - Demyanov,S.V.
TI  - Oncology disease in patients with acute myocardial infarction with nonobstructive coronary atherosclerosis
KW  - инфаркт миокарда
KW  - онкологические заболевания
KW  - статьи в сборниках
N1  - Библиогр.: 5 назв
N2  - The aim of this study was to evaluate the cancer incidence among patients with myocardial
infarction with nonobstructive coronary atherosclerosis (MINOCA). Material and Methods. The
 non-randomized controlled study included patients with acute coronary syndrome (ACS) treated
 between 2010 and 2015. Inclusion criteria comprised NOCA (normal coronary arteries / plaques
 <50%) confirmed by invasive coronary angiography (CAG) and age over 18 years at the time of
 randomization. The exclusion criterion was revascularization of the coronary arteries. We compared
 the study population with patients from POLINCOR study (NCT03122340), which included
 patients with ACS with obstructive CAD confirmed by invasive CAG, who were admitted to the
 department of emergency cardiology in 2015-2016 [5]. Results. Among 5794 patients, who were
 hospitalized with ACS to the Department of Emergency Cardiology in 2010‑2016, 2.8% (161)
 patients demonstrated nonobstructive coronary atherosclerosis confirmed with CAG. One (0.6%)
 patient died. There were 94 (58%) cases with acute myocardial infarction, 27 (17%) with unstable
 angina, 15(9%) with pseudo-coronary scenario of myocarditis, 7 (4%) with cardiomyopathy, and
 16 (10%) with arrhythmias, congenital heart defects, aortic dissection. Among the patients with
 MINOCA, there were 30 (19%) patients with malignant and non-malignant tumors with cancer,
 including 7 (23%) patients with cancer of kidneys, sigmoid colon and cervix. Bladder cancer was
 diagnosed in 1 (0.6%) case before admission to the hospital, and lung cancer was identified in 1
 (0.6%) case at autopsy. The cancer incidence rate in patients with MINOCA was higher than in
 patients with obstructive CAD. Conclusion. The proportion of patients with MINOCA among
 patients with ACS in 2015‑2016 was 2.8 % (161). MINOCA enconpasses a heterogeneous group of
 diseases, including AMI, unstable angina, myocarditis, cardiomyopathy, arrithmia, aortic dissection
 and others. Hospital mortality was 0.6%. The cancer incidence in patients with MINOCA was
 higher than in patients with obstructive CAD
UR  - http://vital.lib.tsu.ru/vital/access/manager/Repository/vtls:000662005
ER  -