TY  - BOOK
AU  - Plattner,Hasso
AU  - Schapranow,Matthieu-P.
ED  - SpringerLink (Online service)
TI  - High-Performance In-Memory Genome Data Analysis: How In-Memory Database Technology Accelerates Personalized Medicine 
T2  - In-Memory Data Management Research,
SN  - 9783319030357
AV  - QH324.2-324.25 
U1  - 570.285 23
PY  - 2014///
CY  - Cham
PB  - Springer International Publishing, Imprint: Springer
KW  - Life Sciences
KW  - Medical records
KW  - Data processing
KW  - Bioinformatics
KW  - Biology
KW  - Genetics
KW  - Mathematics
KW  - Mathematical statistics
KW  - Management information systems
KW  - Computer Appl. in Life Sciences
KW  - Computational Biology/Bioinformatics
KW  - Business Information Systems
KW  - Statistics and Computing/Statistics Programs
KW  - Genetics and Population Dynamics
KW  - Health Informatics
N1  - 1. Innovations for Personalized Medicine -- 2. Modeling Genome Data Processing Pipelines -- 3. Scheduling and Execution of Genome Data processing Pipelines -- 4. Exchanging Medical Knowledge -- 5. Billing Processes in Personalized Medicine -- 6. Real-time Analysis of Patient Cohorts -- 7. Ad-hoc Analysis of Genetic Pathways -- 8. Combined Search in Structured and Unstructured Medical Data -- Real-time Collaboration in the Course of Personalized Medicine
N2  -  Recent achievements in hardware and software developments have enabled the introduction of a revolutionary technology: in-memory data management. This technology supports the flexible and extremely fast analysis of massive amounts of data, such as diagnoses, therapies, and human genome data. This book shares the latest research results of applying in-memory data management to personalized medicine, changing it from computational possibility to clinical reality. The authors provide details on innovative approaches to enabling the processing, combination, and analysis of relevant data in real-time. The book bridges the gap between medical experts, such as physicians, clinicians, and biological researchers, and technology experts, such as software developers, database specialists, and statisticians. Topics covered in this book include - amongst others - modeling of genome data processing and analysis pipelines, high-throughput data processing, exchange of sensitive data and protection of intellectual property. Beyond that, it shares insights on research prototypes for the analysis of patient cohorts, topology analysis of biological pathways, and combined search in structured and unstructured medical data, and outlines completely new processes that have now become possible due to interactive data analyses
UR  - http://dx.doi.org/10.1007/978-3-319-03035-7
ER  -