TY  - BOOK
AU  - Colman,Michael A.
ED  - SpringerLink (Online service)
TI  - Mechanisms of Atrial Arrhythmias: Insights from the Development of a Biophysically Detailed Model of the Human Atria 
T2  - Springer Theses, Recognizing Outstanding Ph.D. Research,
SN  - 9783319016436
AV  - QH505 
U1  - 571.4 23
PY  - 2014///
CY  - Cham
PB  - Springer International Publishing, Imprint: Springer
KW  - physics
KW  - Cardiology
KW  - Biology
KW  - Data processing
KW  - Physics
KW  - Biophysics and Biological Physics
KW  - Computer Appl. in Life Sciences
KW  - Numerical and Computational Physics
KW  - Mathematical Applications in the Physical Sciences
N1  - Introduction -- Background -- Development of a new model for simulating the electrical action potentials of human atrial myocytes -- Development of a family of regional cell models -- Autonomic regulation and pathophysiological remodelling -- 3D Anatomical Modelling of the Atria -- Pacemaking and autonomic regulation in the 3D sinoatrial node and atria -- Atrial Fibrillation -- Discussion
N2  - This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac electrophysiology, physics of excitable media, applied mathematics and high performance scientific computing and visualisation.  The author uses computer models to provide insights into the underlying mechanisms of the genesis of atrial fibrillation and develops novel techniques for the monitoring of atrial tachycardia. 
UR  - http://dx.doi.org/10.1007/978-3-319-01643-6
ER  -