TY  - BOOK
AU  - Kutikhin,Anton G.
AU  - Yuzhalin,Arseniy E.
ED  - SpringerLink (Online service)
TI  - Genomics of Pattern Recognition Receptors: Applications in Oncology and Cardiovascular Diseases 
SN  - 9783034806886
AV  - QH345 
U1  - 572.696 23
PY  - 2013///
CY  - Basel
PB  - Springer Basel, Imprint: Springer
KW  - Life Sciences
KW  - Oncology
KW  - Human genetics
KW  - Immunology
KW  - Cardiology
KW  - Cell receptors
KW  - Receptors
KW  - Cancer Research
KW  - Human Genetics
N1  - The Biology of Toll-like Receptors and NOD-like Receptors: Toggles of Inflammation -- Pattern Recognition Receptors, Gene Polymorphisms, and Cancer: A Double-Edged Sword -- Structural Genomic Variation in Toll-Like Receptor 4 and Cancer -- Structural Genomic Variation in Other Toll-like Receptors and Cancer -- Structural Genomic Variation in Toll-Like Receptor Signaling Pathway and Cancer -- Structural Genomic Variation in Toll-like Receptor Pathway and Prostate Cancer -- Structural Genomic Variation in NOD-Like Receptors and Cancer -- Structural Genomic Variation in Pattern Recognition Receptors and Cardiovascular Diseases -- Hot Spots In the Field: Where Should We Go
N2  - This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed
UR  - http://dx.doi.org/10.1007/978-3-0348-0688-6
ER  -