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Quantifying lens elastic properties with optical coherence elastography as a function of intraocular pressure C. Wu, H. Zhang, M. Singh [et al.]

Contributor(s): Zhang, Hongqiu | Singh, Manmohan | Aglyamov, Salavat R | Larin, Kirill V | Wu, ChenMaterial type: ArticleArticleSubject(s): оптическая когерентная эластография | внутриглазное давление | хрусталик глазаGenre/Form: статьи в журналах Online resources: Click here to access online In: Proceedings of SPIE Vol. 10880 : Optical elastography and tissue biomechanics VI. P. 108801P-1-108801P-5Abstract: Normal intraocular pressure (IOP) is crucial for proper maintaining of eye-globe geometry, ocular tissue health, and visual acuity. An elevated IOP is associated with diseases such as glaucoma and uveitis. While the effects of an elevated IOP on the delicate tissues of the optic nerve head and retina are well-studied, the changes in lenticular biomechanical properties as a function of IOP are not as clear. Moreover, changes in lenticular biomechanical properties have been implicated in conditions and diseases such as presbyopia and cataract. However, measuring the biomechanical properties of the lens as it sits inside the eye-globe is a challenge, but it is necessary to correctly understand the interplay between lenticular biomechanical properties and IOP. In this work, we utilized optical coherence elastography (OCE) to measure the biomechanical properties of the porcine lens in situ.
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Normal intraocular pressure (IOP) is crucial for proper maintaining of eye-globe geometry, ocular tissue health, and visual acuity. An elevated IOP is associated with diseases such as glaucoma and uveitis. While the effects of an elevated IOP on the delicate tissues of the optic nerve head and retina are well-studied, the changes in lenticular biomechanical properties as a function of IOP are not as clear. Moreover, changes in lenticular biomechanical properties have been implicated in conditions and diseases such as presbyopia and cataract. However, measuring the biomechanical properties of the lens as it sits inside the eye-globe is a challenge, but it is necessary to correctly understand the interplay between lenticular biomechanical properties and IOP. In this work, we utilized optical coherence elastography (OCE) to measure the biomechanical properties of the porcine lens in situ.

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