Role of cAMP- and IKK-2-dependent signaling pathways in functional stimulation of mesenchymal progenitor cells with alkaloid songorine G. N. Zyu'kov, V. V. Zhdanov, E. V. Udut [et.al.]
Material type: ArticleSubject(s): клетки-предшественники | мезенхимальные клеткиGenre/Form: статьи в журналах Online resources: Click here to access online In: Bulletin of experimental biology and medicine Vol. 159, № 5. P. 642-645Abstract: The role of cAMP- and IKK-2-dependent pathways in stimulation of the growth capacity of mesenchymal progenitor cells with alkaloid songorine was studied in vitro. Inhibitors of adenylate cyclase and IKK-2 were shown to abolish the increase in proliferative activity of progenitor cells. Moreover, blockade of the inhibitory kinase complex was accompanied by a decrease in the intensity of progenitor cell differentiation.Библиогр.: 15 назв.
The role of cAMP- and IKK-2-dependent pathways in stimulation of the growth capacity of mesenchymal progenitor cells with alkaloid songorine was studied in vitro. Inhibitors of adenylate cyclase and IKK-2 were shown to abolish the increase in proliferative activity of progenitor cells. Moreover, blockade of the inhibitory kinase complex was accompanied by a decrease in the intensity of progenitor cell differentiation.
There are no comments on this title.