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Cancer Targeted Drug Delivery (Record no. 356857)
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| 000 -Маркер записи | |
|---|---|
| Контрольное поле постоянной длины | 05112nam a22004815i 4500 |
| 001 - Контрольный номер | |
| Контрольное поле | vtls000483921 |
| 005 - Дата корректировки | |
| Контрольное поле | 20210922065819.0 |
| 007 - Кодируемые данные (физ. описан.) | |
| Контрольное поле постоянной длины | cr nn 008mamaa |
| 008 - Кодируемые данные | |
| Контрольное поле постоянной длины | 140715s2013 xxu| s |||| 0|eng d |
| 020 ## - Индекс ISBN | |
| ISBN | 9781461478768 |
| -- | 978-1-4614-7876-8 |
| 024 7# - Прочие стандартные номера | |
| Стандартный номер | 10.1007/978-1-4614-7876-8 |
| Источник номера | doi |
| 035 ## - Системный контрольный номер | |
| Системный контрольный номер | to000483921 |
| 040 ## - Источник каталогиз. | |
| Служба первич. каталог. | Springer |
| Служба, преобразующая запись | Springer |
| Организация, изменившая запись | RU-ToGU |
| 050 #4 - Расстановочный код библ. Конгресса | |
| Классификационный индекс | RS380 |
| 050 #4 - Расстановочный код библ. Конгресса | |
| Классификационный индекс | RS190-210 |
| 072 #7 - Код предметной/темат. категории | |
| Код предметной/темат. категории | TDCW |
| Источник кода | bicssc |
| 072 #7 - Код предметной/темат. категории | |
| Код предметной/темат. категории | MED072000 |
| Источник кода | bisacsh |
| 082 04 - Индекс Дьюи | |
| Индекс Дьюи | 615.19 |
| Номер издания | 23 |
| 100 1# - Автор | |
| Автор | Bae, You Han. |
| Роль лиц | editor. |
| 9 (RLIN) | 414682 |
| 245 10 - Заглавие | |
| Заглавие | Cancer Targeted Drug Delivery |
| Физический носитель | [electronic resource] : |
| Продолж. заглавия | An Elusive Dream / |
| Ответственность | edited by You Han Bae, Randall J. Mrsny, Kinam Park. |
| 260 ## - Выходные данные | |
| Место издания | New York, NY : |
| Издательство | Springer New York : |
| -- | Imprint: Springer, |
| Дата издания | 2013. |
| 300 ## - Физическое описание | |
| Объем | XVII, 720 p. 117 illus., 86 illus. in color. |
| Иллюстрации/тип воспроизводства | online resource. |
| 336 ## - Тип содержимого | |
| Тип содержимого | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - Средство доступа | |
| Средство доступа | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - Тип носителя | |
| Тип носителя | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 505 0# - Примечание о содержании | |
| Содержание | A Time Travel Journey Through Cancer Therapies -- Nanotechnology for Cancer Treatment: Possibilities & Limitations -- Vascular Targeting Approaches to Treat Cancer -- Tumor Immunotherapy by Utilizing a Double-Edged Sword Chemokines -- Cancer Biology: Some Causes for a Variety of Different Diseases -- Cancer Stromal Targeting (CAST) Therapy and Tailored Antibody Drug Conjugate Therapy Depending on Nature of Tumor Stroma -- Cancer Cell Respiration: Hypoxia and pH in Solid Tumors -- Tumor Vasculature, EPR Effect, and Anticancer Nanomedicine: Connecting the Dots -- Pressure Gradients in Solid Tumors -- The ADAMs: New Therapeutic Targets for Cancer? -- Role of the Extracellular Matrix – Enzyme Activities and Metastasis -- The Role of Non-Cancerous Cells in Cancer: Pancreatic Ductal Adenocarcinoma as Model to Understand the Impact of Tumor Microenvironment on Epithelial Carcinogenesis -- Heterogeneity of Cancers and its Implication for Targeted Drug Delivery -- A Study of Cancer Heterogeneity: From Genetic Instability to Epigenetic Diversity in Colorectal Cancer -- Nanotherapeutics in Multidrug Resistance -- Stem Cells and Cancer -- Mechanisms of Metastasis -- Cancer-Specific Ligand/Receptor Interactions -- Targeting Drugs to Cancer: A Tough Journey to the Tumor Cell -- Long Circulation and Tumor Accumulation -- Convective and Diffusive Transport in Drug Delivery -- Intravital Real-Time Confocal Laser Scanning Microscopy for the in Situ Evaluation of Nanocarriers -- The EPR effect in Cancer Therapy -- In Vitro 3-dimensional Cancer Culture Model -- Complex Transport Around Tumor: Need for Realistic In Vitro Tumor Transport Model -- The Missing Components Today and the New Treatments Tomorrow. |
| 520 ## - Аннотация | |
| Аннотация | This book was conceived from a simple question as to why cancer is so difficult to treat. Ultimately we want to find ways to cure cancers, but that may be an elusive dream at least with the technologies we have now and expect to have in the near future. This leads the question of whether it is possible to improve current cancer treatment methods, especially from the perspective of enhancing targeted drug delivery to tumors. This volume is designed to provide information related to the difficulties in treating cancers through targeted drug delivery, our current understanding of cancer biology, and potential technologies that might be used to achieve enhanced drug delivery to tumors. An ideal drug delivery system for treating cancers would maximize the therapeutic efficacy with minimal side effects in clinical applications. The seemingly improved anticancer efficacy of the current nanoparticle-based formulations needs to be viewed from the context of very poor success rates for translation to human applications. The results of in vitro cell culture models and small animal in vivo experiments have not been extrapolated to clinical applications. Finding the reasons for the lack of successful translation is required if we are to discover approaches to substantially extend the survival time of cancer patients, and hopefully identify cures. Cancer Targeted Drug Delivery: Elusive Dream describes some answers of achieving the so far elusive dream of treating cancers like other chronic diseases with therapies that focus using improved drug delivery systems designed to better align with the unique biological and physiological properties of cancer. |
| 650 #0 - Тематические рубрики | |
| Основная рубрика | medicine. |
| 9 (RLIN) | 566220 |
| 650 #0 - Тематические рубрики | |
| Основная рубрика | Toxicology. |
| 9 (RLIN) | 302218 |
| 650 #0 - Тематические рубрики | |
| Основная рубрика | Pharmaceutical technology. |
| 9 (RLIN) | 410704 |
| 650 14 - Тематические рубрики | |
| Основная рубрика | Biomedicine. |
| 9 (RLIN) | 566246 |
| 650 24 - Тематические рубрики | |
| Основная рубрика | Pharmaceutical Sciences/Technology. |
| 9 (RLIN) | 329108 |
| 650 24 - Тематические рубрики | |
| Основная рубрика | Pharmacology/Toxicology. |
| 9 (RLIN) | 302222 |
| 700 1# - Другие авторы | |
| Другие авторы | Mrsny, Randall J. |
| Роль лиц | editor. |
| 9 (RLIN) | 414683 |
| 700 1# - Другие авторы | |
| Другие авторы | Park, Kinam. |
| Роль лиц | editor. |
| 9 (RLIN) | 414684 |
| 710 2# - Другие организации | |
| Организация/юрисдикция | SpringerLink (Online service) |
| 9 (RLIN) | 143950 |
| 773 0# - Источник информации | |
| Название источника | Springer eBooks |
| 856 40 - Электронный адрес документа | |
| URL | <a href="http://dx.doi.org/10.1007/978-1-4614-7876-8">http://dx.doi.org/10.1007/978-1-4614-7876-8</a> |
| 912 ## - Coursera for Campus: онлайн курсы для ТГУ | |
| Coursera for Campus: онлайн курсы для ТГУ | ZDB-2-SBL |
| 999 ## - Системные контрольные номера (Koha) | |
| biblionumber (Koha) | 356857 |
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